The OffCourse Big Band has collaborated with eminent musicians who have enriched its performances. A special relationship, with a continuous contribution, was born with many artists:
- Sara Jane Ghiotti
- Massimo Morganti
- Roberto Monti
- Marco Postacchini
- Elio Lucarelli
- Manuela Evelyn Prioli
- Valerio Barbieri
- Luca Bolognesi
- Renato Pignieri
- Manuel Cilio
- Marco Collazzoni